Department of Pathology and Laboratory Medicine Reflex Test List 2025

Cleveland Clinic Laboratories' 2025 Reflex Test List documents its ANA follow-up cascades: a positive ANA by IFA reflexes to ANAS plus DNA antibody with confirmation and an ENA antibody panel; a positive EIA ANA screen triggers the same reflex set. Candidate notes: ANA by IFA Reflex (PANEL): if ANA by IFA is positive, reflex to ANAS + DNA antibody with confirmation + ENA panel (SSA, SSB, Smith, JO-1, chromatin, scleroderma, RNP, ribosomal RNP, centromere) ANA Panel I (ANA1): if ANA screen by EIA is positive, same DNA-antibody and ENA-panel reflex is performed Reflex tests are performed and billed in addition to the screen Limits noted in the record: Administrative list: gives the reflex cascade structure but no interpretation guidance on titer cutoffs or pattern associations Only covers Cleveland Clinic's internal ANA reflex pathways, not general ANA interpretation A positive ANA is not a diagnosis. Claims in this record are not verified.

A positive ANA is not a diagnosis. Claims in this record are not verified.

source